When a cell is dividing the chromosomes are duplicated into two identical clusters. Between these clusters is a cleavage furrow, which forms the cell nuclei and separates the cell into two daughter cells. Daniel Gerlich has discovered that when something goes wrong in this process the cleavage furrow regresses and the cell does not divide creating a tetraploid cell. After studying the process Gerlich has found that enzyme Aurora B is very important. Aurora B responds to non-separated chromosomes and is part of a protective mechanism that ensures that the final step of cell division is only initiated when all chromosomes have been fully separated” says Gerlich
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